Barcelona slumped to a 1-0 home defeat by Rayo Vallecano which pushed leaders Real Madrid a step closer to the La Liga title.
The Copa del Rey derby match between Real Betis and Sevilla was suspended after a pole hurled from the stands hit Sevilla player Joan Jordan in the head on Saturday.
Zlatan Ibrahimovic matched a Cristiano Ronaldo record as depleted AC Milan won 3-0 at 10-man Venezia to move top of Serie A on Sunday.
La Liga champions Atletico Madrid were stunned by Granada, losing 2-1 on Wednesday, while Napoli slipped to defeat against Spezia in Serie A.
Serie A leaders Napoli lost for the first time this season as Inter Milan reinvigorated their own title bid with a 3-2 win at the San Siro.
Bayern Munich beat Werder Bremen 3-1 with Robert Lewandowski climbing to second in the Bundesliga's all-time scorers list, as Real Madrid defeated Elche 2-1.